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4. Financial assets

Fair values

The following table presents the Group’s assets that are measured at fair value through profit and loss at December 31 (in CHF 1 000):

2022

 

Level 1

 

Level 2

 

Level 3

 

Total

Assets

 

 

 

 

 

 

 

 

Securities

 

 

 

 

 

 

 

 

– Shares

 

3 035 170

 

 

16 179

 

3 051 349

– Derivative instruments

 

 

 

 

Total assets

 

3 035 170

 

 

16 179

 

3 051 349

 

 

 

 

 

 

 

 

 

2021

 

 

 

 

 

 

 

 

Assets

 

 

 

 

 

 

 

 

Securities

 

 

 

 

 

 

 

 

– Shares

 

3 638 890

 

 

 

3 638 890

– Derivative instruments

 

 

 

2 222

 

2 222

Total assets

 

3 638 890

 

 

2 222

 

3 641 112

The fair value of financial instruments traded in active markets is based on quoted market prices at the balance sheet date. A market is regarded as active if quoted prices are readily and regularly available and those prices represent actual and regularly occurring market transactions on an arm’s length basis. The quoted market price used for financial assets held by the Group is the closing price. These instruments are included in level 1.

The fair value of financial instruments that are not traded in an active market is determined by using valuation techniques. These valuation techniques maximize the use of observable market data where it is available. The options are valued on the basis of the Black-Scholes model which is based on market conditions existing at each balance sheet date. These instruments are included in level 2.

If one or more of the significant inputs is not based on observable market data, the instrument is included in level 3. The valuation of level 3 instruments is quarterly reviewed. As soon as new or adjusted parameters are available the valuation model (e.g. earnings multiple model) of unlisted shares is adjusted accordingly. As of December 31, 2022, the Company holds one level 3 instrument (December 31, 2021: one).

The table below summarizes the transactions in level 3 instruments (in CHF 1 000):

 

 

2022

 

2021

Opening balance

 

2 222

 

2 155

Purchases

 

16 875

 

Sales

 

(5 071)

 

Realized gains/(losses) included in net gain/loss from securities

 

2 849

 

Unrealized gains/(losses) included in net gain/loss from securities

 

(697)

 

67

Closing balance

 

16 179

 

2 222

Gains/(losses) on level 3 instruments included in net gain/loss from securities

 

2 152

 

67

There have been no transfers between level 1, 2 and 3 during the reporting period. No sensitivity analysis has been disclosed due to the immaterial amount of level 3 instruments.

The level 3 instrument as at December 31, 2021, (Valuation: TCHF 2 222) was allocated as part of a corporate action in 2019 and sold at a value of TCHF 5 071 in March 2022.

The fair value of the level 3 instrument at initial recognition represents the transaction price (purchase of Series B-1 Preferred Stock of Rivus Pharmaceuticals in August 2022 for TCHF 16 875), which was paid in a financing round together with other investors. For the valuation as at December 31, 2022, it is deemed to be appropriate to use the transaction price in USD, as it is a reasonable approximation of fair value at the valuation date given the fact that no events occurred which significantly impact the fair value.

In August 2022, 8 733 538 Contingent Value Rights were allocated from a corporate action. The valuation as of December 31, 2022, is CHF 0.

For assets and liabilities carried at amortized cost, their carrying values are a reasonable approximation of fair value.

Securities

The changes in value of securities by investment category are as follows (in CHF 1 000):

 

 

Listed shares

 

Unlisted shares

 

Derivative instruments

 

Total

Opening balance as at 01.01.2021 at fair values

 

3 952 504

 

 

2 155

 

3 954 659

Purchases

 

955 515

 

 

 

955 515

Sales

 

(925 467)

 

 

 

(925 467)

Net gains/(losses) from securities

 

(343 662)

 

 

67

 

(343 595)

Realized gains

 

312 779

 

 

 

312 779

Realized losses

 

(1 831)

 

 

(2 330)

 

(4 161)

Unrealized gains

 

437 584

 

 

67

 

437 651

Unrealized losses

 

(1 092 194)

 

 

2 330

 

(1 089 864)

Closing balance as at 31.12.2021 at fair values

 

3 638 890

 

 

2 222

 

3 641 112

 

 

 

 

 

 

 

 

 

Opening balance as at 01.01.2022 at fair values

 

3 638 890

 

 

2 222

 

3 641 112

Purchases

 

183 812

 

16 875

 

 

200 687

Sales

 

(471 115)

 

 

(5 071)

 

(476 186)

Net gains/(losses) from securities

 

(316 417)

 

(697)

 

2 849

 

(314 265)

Realized gains

 

47 563

 

 

2 849

 

50 412

Realized losses

 

(79 326)

 

 

 

(79 326)

Unrealized gains

 

437 200

 

 

 

437 200

Unrealized losses

 

(721 854)

 

(697)

 

 

(722 551)

Closing balance as at 31.12.2022 at fair values

 

3 035 170

 

16 179

 

 

3 051 349

Securities comprise the following:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Company

 

Number 31.12.2021

 

Change

 

Number 31.12.2022

 

Market price in original currency 31.12.2022

 

Valuation CHF mn 31.12.2022

 

Valuation CHF mn 31.12.2021

Ionis Pharmaceuticals

 

10 232 973

 

(597 973)

 

9 635 000

 

USD

 

37.77

 

336.4

 

284.3

Argenx SE

 

970 538

 

(78 035)

 

892 503

 

USD

 

378.83

 

312.6

 

310.3

Neurocrine Biosciences

 

3 015 400

 

(285 400)

 

2 730 000

 

USD

 

119.44

 

301.5

 

234.5

Moderna

 

1 663 349

 

(161 398)

 

1 501 951

 

USD

 

179.62

 

249.4

 

385.7

Vertex Pharmaceuticals

 

1 030 000

 

(99 477)

 

930 523

 

USD

 

288.78

 

248.4

 

206.5

Incyte

 

2 897 000

 

(5 923)

 

2 891 077

 

USD

 

80.32

 

214.7

 

194.1

Alnylam Pharmaceuticals

 

1 110 000

 

(220 000)

 

890 000

 

USD

 

237.65

 

195.5

 

171.8

Intra-Cellular Therapies

 

3 538 419

 

(246 940)

 

3 291 479

 

USD

 

52.92

 

161.0

 

169.1

Myovant Sciences

 

6 122 039

 

(249 400)

 

5 872 639

 

USD

 

26.96

 

146.4

 

87.0

Revolution Medicines

 

3 421 462

 

1 356 100

 

4 777 562

 

USD

 

23.82

 

105.2

 

78.6

Agios Pharmaceuticals

 

4 312 292

 

(281 500)

 

4 030 792

 

USD

 

28.08

 

104.6

 

129.4

Sage Therapeutics

 

3 170 104

 

(219 826)

 

2 950 278

 

USD

 

38.14

 

104.0

 

123.1

Celldex Therapeutics

 

 

1 800 000

 

1 800 000

 

USD

 

44.57

 

74.2

 

-

Arvinas

 

2 176 903

 

(40 491)

 

2 136 412

 

USD

 

34.21

 

67.6

 

163.2

Relay Therapeutics

 

4 085 962

 

34 758

 

4 120 720

 

USD

 

14.94

 

56.9

 

114.6

Macrogenics

 

7 275 564

 

1 654 399

 

8 929 963

 

USD

 

6.71

 

55.4

 

106.6

Fate Therapeutics

 

3 701 336

 

1 138 443

 

4 839 779

 

USD

 

10.09

 

45.1

 

197.7

Exelixis

 

2 835 000

 

(180 500)

 

2 654 500

 

USD

 

16.04

 

39.4

 

47.3

Crispr Therapeutics

 

949 584

 

(60 979)

 

888 605

 

USD

 

40.65

 

33.4

 

65.7

Wave Life Sciences

 

4 602 858

 

(108 400)

 

4 494 458

 

USD

 

7.00

 

29.1

 

13.2

Beam Therapeutics

 

606 821

 

86 300

 

693 121

 

USD

 

39.11

 

25.1

 

44.1

Esperion Therapeutics

 

4 477 964

 

(283 900)

 

4 194 064

 

USD

 

6.23

 

24.2

 

20.4

Mersana Therapeutics

 

4 135 000

 

(68 800)

 

4 066 200

 

USD

 

5.86

 

22.0

 

23.5

Kezar Life Sciences

 

4 918 148

 

(1 918 148)

 

3 000 000

 

USD

 

7.04

 

19.5

 

75.1

Essa Pharma

 

5 015 814

 

2 863 769

 

7 879 583

 

USD

 

2.52

 

18.4

 

65.0

Scholar Rock Holding

 

2 275 125

 

(142 400)

 

2 132 725

 

USD

 

9.05

 

17.8

 

51.6

Generation Bio Co.

 

3 853 180

 

(244 900)

 

3 608 280

 

USD

 

3.93

 

13.1

 

24.9

Black Diamond Therapeutics

 

3 440 000

 

1 937 839

 

5 377 839

 

USD

 

1.80

 

8.9

 

16.7

Molecular Templates

 

10 792 003

 

400 000

 

11 192 003

 

USD

 

0.33

 

3.4

 

38.6

Homology Medicines

 

1 737 122

 

(114 600)

 

1 622 522

 

USD

 

1.26

 

1.9

 

5.8

Biogen

 

500 000

 

(500 000)

 

 

USD

 

n.a.

 

 

109.5

Radius Health

 

7 705 714

 

(7 705 714)

 

 

USD

 

n.a.

 

 

48.7

Nektar Therapeutics

 

2 620 676

 

(2 620 676)

 

 

USD

 

n.a.

 

 

32.3

Listed shares

 

 

 

 

 

 

 

 

 

 

 

3 035.2

 

3 638.9

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Rivus Pharmaceuticals

 

 

 

 

 

 

 

USD

 

 

 

16.2

 

Unlisted shares

 

 

 

 

 

 

 

 

 

 

 

16.2

 

Total shares

 

 

 

 

 

 

 

 

 

 

 

3 051.3

 

3 638.9

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Radius Health – Contingent Value Right

 

 

8 733 538

 

8 733 538

 

USD

 

0.00

 

 

Alder Biopharmaceuticals – Contingent Value Right

 

2 766 008

 

(2 766 008)

 

 

USD

 

n.a.

 

 

2.2

Total derivative instruments

 

 

 

 

 

 

 

 

 

 

 

 

2.2

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Total securities

 

 

 

 

 

 

 

 

 

 

 

3 051.3

 

3 641.1

Securities are deposited with Bank Julius Baer & Co. Ltd., Zurich.

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