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Business Report Portfolio at a glance

Portfolio at a glance

Securities as at December 31, 2021

Company

 

Number of securities

 

Change since 31.12.2020

 

Local currency

 

Share price

 

Market value in CHF mn

 

In % of securities

 

In % of shareholders' equity

 

In % of company

Moderna

 

1 663 349

 

(1 191 614)

 

USD

 

253.98

 

385.7

 

10.6%

 

11.7%

 

0.4%

Argenx SE

 

970 538

 

49 206

 

USD

 

350.19

 

310.3

 

8.5%

 

9.5%

 

1.9%

Ionis Pharmaceuticals

 

10 232 973

 

2 012 973

 

USD

 

30.43

 

284.3

 

7.8%

 

8.7%

 

7.2%

Neurocrine Biosciences

 

3 015 400

 

(19 600)

 

USD

 

85.17

 

234.5

 

6.4%

 

7.1%

 

3.2%

Vertex Pharmaceuticals

 

1 030 000

 

130 000

 

USD

 

219.60

 

206.5

 

5.7%

 

6.3%

 

0.4%

Fate Therapeutics

 

3 701 336

 

1 671 336

 

USD

 

58.51

 

197.7

 

5.4%

 

6.0%

 

3.9%

Incyte

 

2 897 000

 

(3 000)

 

USD

 

73.40

 

194.1

 

5.3%

 

5.9%

 

1.3%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Alnylam Pharmaceuticals

 

1 110 000

 

(45 000)

 

USD

 

169.58

 

171.8

 

4.7%

 

5.2%

 

0.9%

Intra-Cellular Therapies

 

3 538 419

 

 

USD

 

52.34

 

169.1

 

4.6%

 

5.1%

 

4.3%

Arvinas

 

2 176 903

 

 

USD

 

82.14

 

163.2

 

4.5%

 

5.0%

 

4.1%

Agios Pharmaceuticals

 

4 312 292

 

153 390

 

USD

 

32.87

 

129.4

 

3.6%

 

3.9%

 

7.9%

Sage Therapeutics

 

3 170 104

 

1 630 000

 

USD

 

42.54

 

123.1

 

3.4%

 

3.7%

 

5.4%

Relay Therapeutics

 

4 085 962

 

2 676 605

 

USD

 

30.71

 

114.6

 

3.1%

 

3.5%

 

3.8%

Biogen

 

500 000

 

(37 000)

 

USD

 

239.92

 

109.5

 

3.0%

 

3.3%

 

0.3%

Macrogenics

 

7 275 564

 

2 460 000

 

USD

 

16.05

 

106.6

 

2.9%

 

3.2%

 

11.9%

Myovant Sciences

 

6 122 039

 

1 365 000

 

USD

 

15.57

 

87.0

 

2.4%

 

2.6%

 

6.6%

Revolution Medicines

 

3 421 462

 

3 421 462

 

USD

 

25.17

 

78.6

 

2.2%

 

2.4%

 

4.6%

Kezar Life Sciences

 

4 918 148

 

385 000

 

USD

 

16.72

 

75.1

 

2.1%

 

2.3%

 

9.2%

Crispr Therapeutics

 

949 584

 

48 700

 

USD

 

75.78

 

65.7

 

1.8%

 

2.0%

 

1.2%

Essa Pharma

 

5 015 814

 

5 015 814

 

USD

 

14.20

 

65.0

 

1.8%

 

2.0%

 

11.4%

Scholar Rock Holding

 

2 275 125

 

19 474

 

USD

 

24.84

 

51.6

 

1.4%

 

1.6%

 

6.5%

Radius Health

 

7 705 714

 

250 000

 

USD

 

6.92

 

48.7

 

1.3%

 

1.5%

 

16.3%

Exelixis

 

2 835 000

 

 

USD

 

18.28

 

47.3

 

1.3%

 

1.4%

 

0.9%

Beam Therapeutics

 

606 821

 

210 000

 

USD

 

79.69

 

44.1

 

1.2%

 

1.3%

 

0.9%

Molecular Templates

 

10 792 003

 

4 411 672

 

USD

 

3.92

 

38.6

 

1.1%

 

1.2%

 

19.2%

Nektar Therapeutics

 

2 620 676

 

 

USD

 

13.51

 

32.3

 

0.9%

 

1.0%

 

1.4%

Generation Bio Co.

 

3 853 180

 

1 520 000

 

USD

 

7.08

 

24.9

 

0.7%

 

0.8%

 

6.8%

Mersana Therapeutics

 

4 135 000

 

2 250 000

 

USD

 

6.22

 

23.5

 

0.6%

 

0.7%

 

5.8%

Esperion Therapeutics

 

4 477 964

 

530 000

 

USD

 

5.00

 

20.4

 

0.6%

 

0.6%

 

7.1%

Black Diamond Therapeutics

 

3 440 000

 

2 050 000

 

USD

 

5.33

 

16.7

 

0.5%

 

0.5%

 

9.5%

Wave Life Sciences

 

4 602 858

 

2 000 000

 

USD

 

3.14

 

13.2

 

0.4%

 

0.4%

 

7.8%

Homology Medicines

 

1 737 122

 

 

USD

 

3.64

 

5.8

 

0.2%

 

0.2%

 

3.0%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Alder Biopharmaceuticals – Contingent Value Right

 

2 766 008

 

 

USD

 

0.88

 

2.2

 

0.1%

 

0.1%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Total securities

 

 

 

 

 

 

 

 

 

3 641.1

 

100.0%

 

110.9%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Other assets

 

 

 

 

 

 

 

 

 

3.0

 

 

 

0.1%

 

 

Other payables

 

 

 

 

 

 

 

 

 

(360.6)

 

 

 

(11.0%)

 

 

Net asset value

 

 

 

 

 

 

 

 

 

3 283.5

 

 

 

100.0%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Exchange rate as at 31.12.2021: USD/CHF: 0.9129

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