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Portfolio at a glance

Securities as at March 31, 2021

Company

 

Number of securities

 

Change since 31.12.2020

 

Local currency

 

Share price

 

Market value in CHF mn

 

In % of securities

 

In % of shareholders' equity

 

In % of company

Ionis Pharmaceuticals

 

8 166 962

 

(53 038)

 

USD

 

44.96

 

346.5

 

8.1%

 

8.8%

 

5.8%

Moderna

 

2 700 000

 

(154 963)

 

USD

 

130.95

 

333.6

 

7.8%

 

8.5%

 

0.7%

Neurocrine Biosciences

 

2 915 400

 

(119 600)

 

USD

 

97.25

 

267.5

 

6.3%

 

6.8%

 

3.1%

Argenx SE

 

930 538

 

9 206

 

USD

 

275.39

 

241.8

 

5.7%

 

6.2%

 

1.8%

Incyte

 

2 897 000

 

(3 000)

 

USD

 

81.27

 

222.2

 

5.2%

 

5.7%

 

1.3%

Agios Pharmaceuticals

 

4 494 992

 

336 090

 

USD

 

51.64

 

219.0

 

5.1%

 

5.6%

 

6.5%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Alexion Pharmaceuticals

 

1 294 428

 

 

USD

 

152.91

 

186.8

 

4.4%

 

4.8%

 

0.6%

Vertex Pharmaceuticals

 

900 000

 

 

USD

 

214.89

 

182.5

 

4.3%

 

4.7%

 

0.3%

Fate Therapeutics

 

2 161 336

 

131 336

 

USD

 

82.45

 

168.2

 

3.9%

 

4.3%

 

2.3%

Macrogenics

 

5 070 564

 

255 000

 

USD

 

31.85

 

152.4

 

3.6%

 

3.9%

 

9.0%

Alnylam Pharmaceuticals

 

1 130 000

 

(25 000)

 

USD

 

141.19

 

150.5

 

3.5%

 

3.8%

 

1.0%

Radius Health

 

7 455 714

 

 

USD

 

20.86

 

146.8

 

3.4%

 

3.7%

 

15.9%

Biogen

 

537 000

 

 

USD

 

279.75

 

141.8

 

3.3%

 

3.6%

 

0.4%

Arvinas

 

2 056 903

 

(120 000)

 

USD

 

66.10

 

128.3

 

3.0%

 

3.3%

 

4.2%

Sage Therapeutics

 

1 775 104

 

235 000

 

USD

 

74.85

 

125.4

 

2.9%

 

3.2%

 

3.0%

Halozyme Therapeutics

 

2 936 966

 

(1 033 034)

 

USD

 

41.69

 

115.5

 

2.7%

 

2.9%

 

2.0%

Intra-Cellular Therapies

 

3 538 419

 

 

USD

 

33.93

 

113.3

 

2.6%

 

2.9%

 

4.4%

Crispr Therapeutics

 

969 584

 

68 700

 

USD

 

121.85

 

111.5

 

2.6%

 

2.8%

 

1.3%

Esperion Therapeutics

 

3 947 964

 

 

USD

 

28.05

 

104.5

 

2.4%

 

2.7%

 

14.1%

Scholar Rock Holding

 

2 100 125

 

(155 526)

 

USD

 

50.66

 

100.4

 

2.3%

 

2.6%

 

6.1%

Myovant Sciences

 

5 147 039

 

390 000

 

USD

 

20.58

 

100.0

 

2.3%

 

2.6%

 

5.7%

Molecular Templates

 

8 116 105

 

1 735 774

 

USD

 

12.62

 

96.6

 

2.3%

 

2.5%

 

14.5%

Generation Bio Co.

 

2 393 180

 

60 000

 

USD

 

28.46

 

64.3

 

1.5%

 

1.6%

 

4.2%

Relay Therapeutics

 

1 931 344

 

521 987

 

USD

 

34.57

 

63.0

 

1.5%

 

1.6%

 

2.1%

Exelixis

 

2 835 000

 

 

USD

 

22.59

 

60.4

 

1.4%

 

1.5%

 

0.9%

Black Diamond Therapeutics

 

2 230 000

 

840 000

 

USD

 

24.26

 

51.0

 

1.2%

 

1.3%

 

6.2%

Essa Pharma

 

1 825 814

 

1 825 814

 

USD

 

29.05

 

50.0

 

1.2%

 

1.3%

 

4.7%

Nektar Therapeutics

 

2 620 676

 

 

USD

 

20.00

 

49.5

 

1.2%

 

1.3%

 

1.4%

Revolution Medicines

 

1 007 770

 

1 007 770

 

USD

 

45.88

 

43.6

 

1.0%

 

1.1%

 

1.4%

Beam Therapeutics

 

566 821

 

170 000

 

USD

 

80.04

 

42.8

 

1.0%

 

1.1%

 

0.9%

Mersana Therapeutics

 

2 760 000

 

875 000

 

USD

 

16.18

 

42.1

 

1.0%

 

1.1%

 

4.0%

Kezar Life Sciences

 

4 533 148

 

 

USD

 

5.96

 

25.5

 

0.6%

 

0.7%

 

9.4%

Homology Medicines

 

1 737 122

 

 

USD

 

9.41

 

15.4

 

0.4%

 

0.4%

 

3.4%

Wave Life Sciences

 

2 602 858

 

 

USD

 

5.61

 

13.8

 

0.3%

 

0.4%

 

5.3%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Alder Biopharmaceuticals – Contingent Value Right

 

2 766 008

 

 

USD

 

0.88

 

2.3

 

0.1%

 

0.1%

 

 

Bristol-Myers Squibb – Contingent Value Right

 

 

(800 000)

 

USD

 

0.00

 

0.0

 

0.0%

 

0.0%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Total securities

 

 

 

 

 

 

 

 

 

4 278.8

 

100.0%

 

109.2%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Other assets

 

 

 

 

 

 

 

 

 

4.1

 

 

 

0.1%

 

 

Other payables

 

 

 

 

 

 

 

 

 

(364.4)

 

 

 

(9.3%)

 

 

Net asset value

 

 

 

 

 

 

 

 

 

3 918.5

 

 

 

100.0%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

BB Biotech registered shares 1)

 

 

(114 662)

 

 

 

 

 

 

 

 

 

 

 

 

1 Correspond to the total of all own shares held including the second trading line

Exchange rate as at 31.03.2021: USD/CHF: 0.9436

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