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Business Report Portfolio at a glance

Portfolio at a glance

Securities as at March 31, 2022

Company

 

Number of securities

 

Change since 31.12.2021

 

Local currency

 

Share price

 

Market value in CHF mn

 

In % of securities

 

In % of shareholders' equity

 

In % of company

Ionis Pharmaceuticals

 

9 732 973

 

(500 000)

 

USD

 

37.04

 

332.6

 

10.7%

 

12.0%

 

6.9%

Argenx SE

 

920 538

 

(50 000)

 

USD

 

315.31

 

267.8

 

8.6%

 

9.7%

 

1.7%

Moderna

 

1 583 349

 

(80 000)

 

USD

 

172.26

 

251.6

 

8.1%

 

9.1%

 

0.4%

Neurocrine Biosciences

 

2 865 400

 

(150 000)

 

USD

 

93.75

 

247.8

 

7.9%

 

9.0%

 

3.0%

Vertex Pharmaceuticals

 

980 000

 

(50 000)

 

USD

 

260.97

 

235.9

 

7.6%

 

8.5%

 

0.4%

Incyte

 

2 756 000

 

(141 000)

 

USD

 

79.42

 

201.9

 

6.5%

 

7.3%

 

1.2%

Intra-Cellular Therapies

 

3 358 419

 

(180 000)

 

USD

 

61.19

 

189.6

 

6.1%

 

6.9%

 

3.6%

Alnylam Pharmaceuticals

 

1 050 000

 

(60 000)

 

USD

 

163.29

 

158.2

 

5.1%

 

5.7%

 

0.9%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Arvinas

 

2 106 903

 

(70 000)

 

USD

 

67.30

 

130.8

 

4.2%

 

4.7%

 

4.0%

Fate Therapeutics

 

3 511 336

 

(190 000)

 

USD

 

38.77

 

125.6

 

4.0%

 

4.5%

 

3.6%

Agios Pharmaceuticals

 

4 092 292

 

(220 000)

 

USD

 

29.11

 

109.9

 

3.5%

 

4.0%

 

7.5%

Relay Therapeutics

 

3 885 962

 

(200 000)

 

USD

 

29.93

 

107.3

 

3.4%

 

3.9%

 

3.6%

Sage Therapeutics

 

3 010 104

 

(160 000)

 

USD

 

33.10

 

91.9

 

2.9%

 

3.3%

 

5.1%

Revolution Medicines

 

3 251 462

 

(170 000)

 

USD

 

25.51

 

76.5

 

2.5%

 

2.8%

 

4.4%

Kezar Life Sciences

 

4 668 148

 

(250 000)

 

USD

 

16.62

 

71.6

 

2.3%

 

2.6%

 

8.2%

Myovant Sciences

 

5 812 039

 

(310 000)

 

USD

 

13.32

 

71.4

 

2.3%

 

2.6%

 

6.2%

Radius Health

 

8 255 714

 

550 000

 

USD

 

8.83

 

67.2

 

2.2%

 

2.4%

 

17.4%

Macrogenics

 

7 275 564

 

 

USD

 

8.81

 

59.1

 

1.9%

 

2.1%

 

11.9%

Exelixis

 

2 695 000

 

(140 000)

 

USD

 

22.67

 

56.4

 

1.8%

 

2.0%

 

0.8%

Crispr Therapeutics

 

902 105

 

(47 479)

 

USD

 

62.77

 

52.2

 

1.7%

 

1.9%

 

1.2%

Molecular Templates

 

10 992 003

 

200 000

 

USD

 

3.45

 

35.0

 

1.1%

 

1.3%

 

19.5%

Beam Therapeutics

 

576 821

 

(30 000)

 

USD

 

57.30

 

30.5

 

1.0%

 

1.1%

 

0.8%

Essa Pharma

 

5 015 814

 

 

USD

 

6.18

 

28.6

 

0.9%

 

1.0%

 

11.4%

Scholar Rock Holding

 

2 165 125

 

(110 000)

 

USD

 

12.89

 

25.7

 

0.8%

 

0.9%

 

6.1%

Generation Bio Co.

 

3 663 180

 

(190 000)

 

USD

 

7.34

 

24.8

 

0.8%

 

0.9%

 

6.4%

Esperion Therapeutics

 

4 257 964

 

(220 000)

 

USD

 

4.64

 

18.2

 

0.6%

 

0.7%

 

6.8%

Nektar Therapeutics

 

2 960 676

 

340 000

 

USD

 

5.39

 

14.7

 

0.5%

 

0.5%

 

1.6%

Mersana Therapeutics

 

3 925 000

 

(210 000)

 

USD

 

3.99

 

14.4

 

0.5%

 

0.5%

 

4.7%

Wave Life Sciences

 

4 562 858

 

(40 000)

 

USD

 

2.00

 

8.4

 

0.3%

 

0.3%

 

7.5%

Black Diamond Therapeutics

 

3 270 000

 

(170 000)

 

USD

 

2.77

 

8.4

 

0.3%

 

0.3%

 

9.0%

Homology Medicines

 

1 647 122

 

(90 000)

 

USD

 

3.04

 

4.6

 

0.1%

 

0.2%

 

2.9%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Total securities

 

 

 

 

 

 

 

 

 

3 118.7

 

100.0%

 

113.0%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Other assets

 

 

 

 

 

 

 

 

 

1.8

 

 

 

0.1%

 

 

Other payables

 

 

 

 

 

 

 

 

 

(359.6)

 

 

 

(13.0%)

 

 

Net asset value

 

 

 

 

 

 

 

 

 

2 760.9

 

 

 

100.0%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Exchange rate as at 31.03.2022: USD/CHF: 0.9225

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