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Portfolio at a glance

Securities as at June 30, 2021

Company

 

Number of securities

 

Change since 31.12.2020

 

Local currency

 

Share price

 

Market value in CHF mn

 

In % of securities

 

In % of shareholders' equity

 

In % of company

Moderna

 

2 450 000

 

(404 963)

 

USD

 

234.98

 

532.5

 

12.2%

 

13.2%

 

0.6%

Ionis Pharmaceuticals

 

9 112 973

 

892 973

 

USD

 

39.89

 

336.3

 

7.7%

 

8.3%

 

6.5%

Argenx SE

 

955 538

 

34 206

 

USD

 

301.07

 

266.1

 

6.1%

 

6.6%

 

1.9%

Neurocrine Biosciences

 

2 915 400

 

(119 600)

 

USD

 

97.32

 

262.4

 

6.0%

 

6.5%

 

3.1%

Incyte

 

2 897 000

 

(3 000)

 

USD

 

84.13

 

225.4

 

5.2%

 

5.6%

 

1.3%

Agios Pharmaceuticals

 

4 304 992

 

146 090

 

USD

 

55.11

 

219.5

 

5.0%

 

5.4%

 

7.0%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Fate Therapeutics

 

2 546 336

 

516 336

 

USD

 

86.79

 

204.4

 

4.7%

 

5.1%

 

2.7%

Vertex Pharmaceuticals

 

1 050 000

 

150 000

 

USD

 

201.63

 

195.8

 

4.5%

 

4.8%

 

0.4%

Alnylam Pharmaceuticals

 

1 110 000

 

(45 000)

 

USD

 

169.52

 

174.1

 

4.0%

 

4.3%

 

0.9%

Biogen

 

500 000

 

(37 000)

 

USD

 

346.27

 

160.1

 

3.7%

 

4.0%

 

0.3%

Macrogenics

 

6 275 564

 

1 460 000

 

USD

 

26.86

 

155.9

 

3.6%

 

3.9%

 

10.5%

Arvinas

 

2 176 903

 

 

USD

 

77.00

 

155.0

 

3.6%

 

3.8%

 

4.4%

Crispr Therapeutics

 

949 584

 

48 700

 

USD

 

161.89

 

142.2

 

3.3%

 

3.5%

 

1.3%

Intra-Cellular Therapies

 

3 488 419

 

(50 000)

 

USD

 

40.82

 

131.7

 

3.0%

 

3.3%

 

4.3%

Radius Health

 

7 455 714

 

 

USD

 

18.24

 

125.8

 

2.9%

 

3.1%

 

15.8%

Sage Therapeutics

 

2 325 104

 

785 000

 

USD

 

56.81

 

122.2

 

2.8%

 

3.0%

 

4.0%

Myovant Sciences

 

5 222 039

 

465 000

 

USD

 

22.77

 

110.0

 

2.5%

 

2.7%

 

5.7%

Relay Therapeutics

 

2 620 962

 

1 211 605

 

USD

 

36.59

 

88.7

 

2.0%

 

2.2%

 

2.8%

Esperion Therapeutics

 

4 477 964

 

530 000

 

USD

 

21.15

 

87.6

 

2.0%

 

2.2%

 

15.9%

Beam Therapeutics

 

606 821

 

210 000

 

USD

 

128.71

 

72.2

 

1.7%

 

1.8%

 

1.0%

Molecular Templates

 

9 542 621

 

3 162 290

 

USD

 

7.82

 

69.0

 

1.6%

 

1.7%

 

17.0%

Essa Pharma

 

2 440 814

 

2 440 814

 

USD

 

28.57

 

64.5

 

1.5%

 

1.6%

 

6.0%

Generation Bio Co.

 

2 453 180

 

120 000

 

USD

 

26.90

 

61.0

 

1.4%

 

1.5%

 

4.3%

Scholar Rock Holding

 

2 275 125

 

19 474

 

USD

 

28.90

 

60.8

 

1.4%

 

1.5%

 

6.6%

Halozyme Therapeutics

 

1 331 966

 

(2 638 034)

 

USD

 

45.41

 

55.9

 

1.3%

 

1.4%

 

0.9%

Revolution Medicines

 

1 805 105

 

1 805 105

 

USD

 

31.74

 

53.0

 

1.2%

 

1.3%

 

2.5%

Exelixis

 

2 835 000

 

 

USD

 

18.22

 

47.8

 

1.1%

 

1.2%

 

0.9%

Nektar Therapeutics

 

2 620 676

 

 

USD

 

17.16

 

41.6

 

1.0%

 

1.0%

 

1.4%

Black Diamond Therapeutics

 

3 440 000

 

2 050 000

 

USD

 

12.19

 

38.8

 

0.9%

 

1.0%

 

9.5%

Mersana Therapeutics

 

2 860 000

 

975 000

 

USD

 

13.58

 

35.9

 

0.8%

 

0.9%

 

4.1%

Kezar Life Sciences

 

4 533 148

 

 

USD

 

5.43

 

22.8

 

0.5%

 

0.6%

 

9.4%

Wave Life Sciences

 

2 602 858

 

 

USD

 

6.66

 

16.0

 

0.4%

 

0.4%

 

5.2%

Homology Medicines

 

1 737 122

 

 

USD

 

7.27

 

11.7

 

0.3%

 

0.3%

 

3.0%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Alder Biopharmaceuticals – Contingent Value Right

 

2 766 008

 

 

USD

 

0.88

 

2.3

 

0.1%

 

0.1%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Total securities

 

 

 

 

 

 

 

 

 

4 349.3

 

100.0%

 

107.5%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Other assets

 

 

 

 

 

 

 

 

 

7.8

 

 

 

0.2%

 

 

Other liabilities

 

 

 

 

 

 

 

 

 

(310.1)

 

 

 

(7.7%)

 

 

Net asset value

 

 

 

 

 

 

 

 

 

4 047.0

 

 

 

100.0%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

BB Biotech registered shares 1)

 

 

(114 662)

 

 

 

 

 

 

 

 

 

 

 

 

1 Correspond to the total of all own shares held including the second trading line

Exchange rate as at 30.06.2021: USD/CHF: 0.9250

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