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Business Report Portfolio at a glance

Portfolio at a glance

Securities as at June 30, 2022

Company

 

Number of securities

 

Change since 31.12.2021

 

Local currency

 

Share price

 

Market value in CHF mn

 

In % of securities

 

In % of shareholders' equity

 

In % of company

Ionis Pharmaceuticals

 

9 541 028

 

(691 945)

 

USD

 

37.02

 

337.3

 

11.8%

 

13.4%

 

6.7%

Argenx SE

 

902 503

 

(68 035)

 

USD

 

378.88

 

326.6

 

11.5%

 

13.0%

 

1.7%

Neurocrine Biosciences

 

2 798 437

 

(216 963)

 

USD

 

97.48

 

260.5

 

9.1%

 

10.3%

 

2.9%

Vertex Pharmaceuticals

 

950 523

 

(79 477)

 

USD

 

281.79

 

255.8

 

9.0%

 

10.2%

 

0.4%

Moderna

 

1 531 951

 

(131 398)

 

USD

 

142.85

 

209.0

 

7.3%

 

8.3%

 

0.4%

Incyte

 

2 691 077

 

(205 923)

 

USD

 

75.97

 

195.3

 

6.8%

 

7.8%

 

1.2%

Intra-Cellular Therapies

 

3 291 479

 

(246 940)

 

USD

 

57.08

 

179.4

 

6.3%

 

7.1%

 

3.5%

Alnylam Pharmaceuticals

 

1 028 929

 

(81 071)

 

USD

 

145.85

 

143.3

 

5.0%

 

5.7%

 

0.9%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Sage Therapeutics

 

2 950 278

 

(219 826)

 

USD

 

32.30

 

91.0

 

3.2%

 

3.6%

 

5.0%

Radius Health

 

8 733 538

 

1 027 824

 

USD

 

10.37

 

86.5

 

3.0%

 

3.4%

 

18.3%

Agios Pharmaceuticals

 

4 030 792

 

(281 500)

 

USD

 

22.17

 

85.4

 

3.0%

 

3.4%

 

7.4%

Arvinas

 

2 065 026

 

(111 877)

 

USD

 

42.09

 

83.0

 

2.9%

 

3.3%

 

3.9%

Fate Therapeutics

 

3 458 536

 

(242 800)

 

USD

 

24.78

 

81.9

 

2.9%

 

3.3%

 

3.6%

Myovant Sciences

 

5 872 639

 

(249 400)

 

USD

 

12.43

 

69.7

 

2.4%

 

2.8%

 

6.2%

Relay Therapeutics

 

3 977 762

 

(108 200)

 

USD

 

16.75

 

63.6

 

2.2%

 

2.5%

 

3.7%

Revolution Medicines

 

3 302 562

 

(118 900)

 

USD

 

19.49

 

61.5

 

2.2%

 

2.4%

 

4.4%

Exelixis

 

2 654 500

 

(180 500)

 

USD

 

20.82

 

52.8

 

1.9%

 

2.1%

 

0.8%

Crispr Therapeutics

 

888 605

 

(60 979)

 

USD

 

60.77

 

51.6

 

1.8%

 

2.0%

 

1.1%

Esperion Therapeutics

 

4 194 064

 

(283 900)

 

USD

 

6.36

 

25.5

 

0.9%

 

1.0%

 

6.7%

Celldex Therapeutics

 

925 000

 

925 000

 

USD

 

26.96

 

23.8

 

0.8%

 

0.9%

 

2.0%

Kezar Life Sciences

 

3 000 000

 

(1 918 148)

 

USD

 

8.27

 

23.7

 

0.8%

 

0.9%

 

5.0%

Generation Bio Co.

 

3 608 280

 

(244 900)

 

USD

 

6.56

 

22.6

 

0.8%

 

0.9%

 

6.3%

Beam Therapeutics

 

568 121

 

(38 700)

 

USD

 

38.71

 

21.0

 

0.7%

 

0.8%

 

0.8%

Macrogenics

 

7 275 564

 

 

USD

 

2.95

 

20.5

 

0.7%

 

0.8%

 

11.9%

Mersana Therapeutics

 

3 866 200

 

(268 800)

 

USD

 

4.62

 

17.1

 

0.6%

 

0.7%

 

4.0%

Essa Pharma

 

4 990 714

 

(25 100)

 

USD

 

3.15

 

15.0

 

0.5%

 

0.6%

 

11.3%

Wave Life Sciences

 

4 494 458

 

(108 400)

 

USD

 

3.25

 

14.0

 

0.5%

 

0.6%

 

5.2%

Scholar Rock Holding

 

2 132 725

 

(142 400)

 

USD

 

5.49

 

11.2

 

0.4%

 

0.4%

 

4.1%

Black Diamond Therapeutics

 

4 694 113

 

1 254 113

 

USD

 

2.46

 

11.0

 

0.4%

 

0.4%

 

12.9%

Molecular Templates

 

11 192 003

 

400 000

 

USD

 

0.91

 

9.7

 

0.3%

 

0.4%

 

19.9%

Homology Medicines

 

1 622 522

 

(114 600)

 

USD

 

1.97

 

3.1

 

0.1%

 

0.1%

 

2.8%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Total securities

 

 

 

 

 

 

 

 

 

2 852.4

 

100.0%

 

113.2%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Other assets

 

 

 

 

 

 

 

 

 

1.9

 

 

 

0.1%

 

 

Other payables

 

 

 

 

 

 

 

 

 

(334.5)

 

 

 

(13.3%)

 

 

Net asset value

 

 

 

 

 

 

 

 

 

2 519.8

 

 

 

100.0%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Exchange rate as at 30.06.2022: USD/CHF: 0.9551

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