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Portfolio at a glance

Securities as at September 30, 2021

Company

 

Number of securities

 

Change since 31.12.2020

 

Local currency

 

Share price

 

Market value in CHF mn

 

In % of securities

 

In % of shareholders' equity

 

In % of company

Moderna

 

1 678 349

 

(1 176 614)

 

USD

 

384.86

 

601.8

 

14.7%

 

15.7%

 

0.4%

Ionis Pharmaceuticals

 

9 112 973

 

892 973

 

USD

 

33.54

 

284.8

 

7.0%

 

7.4%

 

6.5%

Argenx SE

 

955 538

 

34 206

 

USD

 

302.00

 

268.9

 

6.6%

 

7.0%

 

1.9%

Neurocrine Biosciences

 

2 915 400

 

(119 600)

 

USD

 

95.91

 

260.5

 

6.4%

 

6.8%

 

3.1%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Alnylam Pharmaceuticals

 

1 110 000

 

(45 000)

 

USD

 

188.81

 

195.3

 

4.8%

 

5.1%

 

0.9%

Incyte

 

2 897 000

 

(3 000)

 

USD

 

68.78

 

185.6

 

4.5%

 

4.8%

 

1.3%

Agios Pharmaceuticals

 

4 304 992

 

146 090

 

USD

 

46.15

 

185.1

 

4.5%

 

4.8%

 

7.3%

Vertex Pharmaceuticals

 

1 050 000

 

150 000

 

USD

 

181.39

 

177.5

 

4.3%

 

4.6%

 

0.4%

Fate Therapeutics

 

3 186 336

 

1 156 336

 

USD

 

59.27

 

176.0

 

4.3%

 

4.6%

 

3.3%

Arvinas

 

2 176 903

 

 

USD

 

82.18

 

166.7

 

4.1%

 

4.3%

 

4.1%

Macrogenics

 

7 075 564

 

2 260 000

 

USD

 

20.94

 

138.0

 

3.4%

 

3.6%

 

11.6%

Biogen

 

500 000

 

(37 000)

 

USD

 

282.99

 

131.8

 

3.2%

 

3.4%

 

0.3%

Sage Therapeutics

 

3 170 104

 

1 630 000

 

USD

 

44.31

 

130.9

 

3.2%

 

3.4%

 

5.4%

Intra-Cellular Therapies

 

3 663 419

 

125 000

 

USD

 

37.28

 

127.2

 

3.1%

 

3.3%

 

4.5%

Myovant Sciences

 

5 722 039

 

965 000

 

USD

 

22.44

 

119.6

 

2.9%

 

3.1%

 

6.2%

Relay Therapeutics

 

3 735 962

 

2 326 605

 

USD

 

31.53

 

109.7

 

2.7%

 

2.9%

 

4.0%

Crispr Therapeutics

 

949 584

 

48 700

 

USD

 

111.93

 

99.0

 

2.4%

 

2.6%

 

1.2%

Radius Health

 

7 705 714

 

250 000

 

USD

 

12.41

 

89.1

 

2.2%

 

2.3%

 

16.3%

Revolution Medicines

 

3 410 105

 

3 410 105

 

USD

 

27.51

 

87.4

 

2.1%

 

2.3%

 

4.6%

Scholar Rock Holding

 

2 275 125

 

19 474

 

USD

 

33.02

 

70.0

 

1.7%

 

1.8%

 

6.6%

Molecular Templates

 

10 792 003

 

4 411 672

 

USD

 

6.71

 

67.5

 

1.6%

 

1.8%

 

19.2%

Generation Bio Co.

 

2 453 180

 

120 000

 

USD

 

25.07

 

57.3

 

1.4%

 

1.5%

 

4.3%

Exelixis

 

2 835 000

 

 

USD

 

21.14

 

55.8

 

1.4%

 

1.5%

 

0.9%

Esperion Therapeutics

 

4 477 964

 

530 000

 

USD

 

12.05

 

50.3

 

1.2%

 

1.3%

 

15.8%

Beam Therapeutics

 

606 821

 

210 000

 

USD

 

87.01

 

49.2

 

1.2%

 

1.3%

 

0.9%

Nektar Therapeutics

 

2 620 676

 

 

USD

 

17.96

 

43.9

 

1.1%

 

1.1%

 

1.4%

Essa Pharma

 

5 015 814

 

5 015 814

 

USD

 

8.00

 

37.4

 

0.9%

 

1.0%

 

11.4%

Kezar Life Sciences

 

4 533 148

 

 

USD

 

8.64

 

36.5

 

0.9%

 

1.0%

 

9.4%

Mersana Therapeutics

 

4 135 000

 

2 250 000

 

USD

 

9.43

 

36.3

 

0.9%

 

0.9%

 

5.8%

Black Diamond Therapeutics

 

3 440 000

 

2 050 000

 

USD

 

8.46

 

27.1

 

0.7%

 

0.7%

 

9.5%

Homology Medicines

 

1 737 122

 

 

USD

 

7.87

 

12.7

 

0.3%

 

0.3%

 

3.0%

Wave Life Sciences

 

2 602 858

 

 

USD

 

4.90

 

11.9

 

0.3%

 

0.3%

 

5.1%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Alder Biopharmaceuticals – Contingent Value Right

 

2 766 008

 

 

USD

 

0.88

 

2.3

 

0.1%

 

0.1%

 

 

Total securities

 

 

 

 

 

 

 

 

 

4 093.1

 

100.0%

 

106.8%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Other assets

 

 

 

 

 

 

 

 

 

1.9

 

 

 

0.0%

 

 

Other liabilities

 

 

 

 

 

 

 

 

 

(261.8)

 

 

 

(6.8%)

 

 

Net asset value

 

 

 

 

 

 

 

 

 

3 833.2

 

 

 

100.0%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Exchange rate as at 30.09.2021: USD/CHF: 0.9317

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