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Business Report Portfolio at a glance

Portfolio at a glance

Securities as at December 31, 2023

Company

Number of securities

Change since 31.12.2022

Local currency

Share price

Market value in CHF mn

In % of securities

In % of shareholders' equity

In % of company

Ionis Pharmaceuticals

8 590 000

(1 045 000)

USD

50.59

365.6

13.9%

15.7%

6.0%

Neurocrine Biosciences

2 410 000

(320 000)

USD

131.76

267.2

10.1%

11.5%

2.5%

Argenx SE

825 000

(67 503)

USD

380.43

264.1

10.0%

11.4%

1.4%

Vertex Pharmaceuticals

640 000

(290 523)

USD

406.89

219.1

8.3%

9.4%

0.2%

Intra-Cellular Therapies

3 040 000

(251 479)

USD

71.62

183.2

7.0%

7.9%

3.2%

Moderna

1 891 075

389 124

USD

99.45

158.2

6.0%

6.8%

0.5%

Alnylam Pharmaceuticals

859 700

(30 300)

USD

191.41

138.5

5.3%

6.0%

0.7%

Revolution Medicines

5 046 700

269 138

USD

28.68

121.8

4.6%

5.2%

3.1%

Incyte

2 150 000

(741 077)

USD

62.79

113.6

4.3%

4.9%

1.0%

Arvinas

2 494 531

358 119

USD

41.16

86.4

3.3%

3.7%

3.7%

Celldex Therapeutics

2 416 296

616 296

USD

39.66

80.6

3.1%

3.5%

4.4%

Macrogenics

9 929 963

1 000 000

USD

9.62

80.4

3.1%

3.5%

16.0%

Agios Pharmaceuticals

4 000 000

(30 792)

USD

22.27

75.0

2.8%

3.2%

7.2%

Sage Therapeutics

3 505 000

554 722

USD

21.67

63.9

2.4%

2.8%

5.8%

Immunocore

965 654

965 654

USD

68.32

55.5

2.1%

2.4%

2.0%

Relay Therapeutics

5 925 000

1 804 280

USD

11.01

54.9

2.1%

2.4%

4.8%

Crispr Therapeutics

880 000

(8 605)

USD

62.60

46.4

1.8%

2.0%

1.1%

Essa Pharma

7 879 583

USD

6.60

43.8

1.7%

1.9%

17.9%

Exelixis

2 000 000

(654 500)

USD

23.99

40.4

1.5%

1.7%

0.6%

Biohaven

1 075 000

1 075 000

USD

42.80

38.7

1.5%

1.7%

1.3%

Scholar Rock Holding

2 132 725

USD

18.80

33.7

1.3%

1.5%

3.0%

Black Diamond Therapeutics

8 517 839

3 140 000

USD

2.81

20.1

0.8%

0.9%

16.5%

Wave Life Sciences

4 494 458

USD

5.05

19.1

0.7%

0.8%

3.8%

Beam Therapeutics

693 121

USD

27.22

15.9

0.6%

0.7%

0.9%

Fate Therapeutics

4 839 779

USD

3.74

15.2

0.6%

0.7%

4.9%

Rivus Pharmaceuticals 1)

USD

14.7

0.6%

0.6%

Esperion Therapeutics

4 194 064

USD

2.99

10.6

0.4%

0.5%

3.7%

Generation Bio Co.

3 608 280

USD

1.65

5.0

0.2%

0.2%

5.5%

Molecular Templates 2)

1 029 820

283 686

USD

3.73

3.2

0.1%

0.1%

19.2%

Radius Health – Contingent Value Right

8 733 538

USD

0.00

0.0

0.0%

0.0%

Total securities

2 634.7

100.0%

113.4%

Other assets

2.4

0.1%

Other payables

(313.9)

(13.5%)

Net Asset Value

2 323.2

100.0%

1Unlisted company

2Share split 1:15 as at August 14, 2023

Exchange rate as at 31.12.2023: USD/CHF: 0.8414

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