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Notes to the consolidated financial statements

1. The Company and its principal activity

1. The Company and its principal activity

BB Biotech AG (the Company) is listed on the SIX Swiss Exchange as well as in the «Prime Standard Segment» of the German Exchange and has its registered office in Schaffhausen, Schwertstrasse 6. Its principal activity is to invest in companies active in the biotechnology industry for the purpose of capital appreciation. The investments are held through its wholly owned subsidiaries.

Company

Capital in CHF 1 000

Capital and voting interest in %

Biotech Focus N.V., Curaçao

11

100

Biotech Growth N.V., Curaçao

11

100

Biotech Invest N.V., Curaçao

11

100

Biotech Target N.V., Curaçao

11

100

2. Accounting policies

2. Accounting policies

The condensed consolidated interim financial statements of the Company and its subsidiary companies (the Group) have been prepared in accordance with International Accounting Standards (IAS) 34 «Interim Financial Reporting», as well as the provisions of the rules of the SIX Swiss Exchange for Investment Companies and should be read in conjunction with the consolidated annual financial statements for the year ended December 31, 2024. The preparation of the condensed consolidated interim financial statements requires management to make assumptions and estimates that have an impact on the balance sheet values and items of the statement of comprehensive income in the current financial period. In certain circumstances, the actual values may diverge from these estimates.

The condensed consolidated interim financial statements have been prepared in accordance with the accounting policies set out in the consolidated annual financial statements.

The following amended standard, valid since January 1, 2025, has been applied in these condensed consolidated interim financial statements:

  • IAS 21 (amended, effective January 1, 2025) – Lack of Exchangeability

The following new and amended standards were approved, but will only be applicable for the Group prospectively and were not early adopted in these condensed consolidated interim financial statements:

  • IFRS 9/IFRS 7 (amended, effective January 1, 2026) – Classification and Measurement of Financial Instruments
  • IFRS 18 (effective January 1, 2027) – Presentation and Disclosure in Financial Statements
  • IFRS 19 (effective January 1, 2027) – Subsidiaries without Public Accountability: Disclosures

The Group assessed the potential impact of the above-mentioned new and amended standards. Based on the analysis, the Group concludes that these new and amended standards have no material impact on the Group’s accounting policies and overall results and financial position.

The following exchange rates have been used for the preparation of these condensed consolidated interim financial statements:

Currency

30.09.2025

31.12.2024

USD

0.79640

0.90740

XCG 1)

0.44742

0.50978

EUR

0.93450

0.94008

GBP

1.07090

1.13560

1since April 1, 2025, Caribbean Guilder, before ANG (Antillean Guilder)

3. Financial assets

3. Financial assets

Fair Values

The following table presents the Group’s assets that are measured at fair value (in CHF 1 000):

30.09.2025

Level 1

Level 2

Level 3

Total

Assets

Securities

- Shares

2 185 004

43 422

2 228 426

- Derivative instruments

104

104

Total assets

2 185 004

104

43 422

2 228 530

31.12.2024

Assets

Securities

- Shares

2 369 436

37 444

2 406 881

- Derivative instruments

Total assets

2 369 436

37 444

2 406 881

The table below summarizes the transactions in level 3 instruments (in CHF 1 000):

01.01.–30.09.2025

01.01.–30.09.2024

Opening balance

37 444

14 725

Purchases

12 079

15 139

Unrealized gains/(losses) included in gains/losses from securities

(6 101)

5 030

Closing balance

43 422

34 894

Gains/(losses) on level 3 instruments included in gains/losses from securities

(6 101)

5 030

There were no transfers between level 1, 2 and 3 during the reporting period.

The fair value of level 3 instruments at initial recognition represents the transaction price (purchase of preferred stocks of Rivus Pharmaceuticals in August 2022 for TCHF 16 875, August 2024 for TCHF 15 139 and January 2025 for TCHF 12 079), which was paid in financing rounds together with other investors. For the valuation as at September 30, 2025, it is deemed to be appropriate to use the latest transaction price in USD, as it is a reasonable approximation of fair value at the valuation date, based on the information available and in the absence of developments that would reasonably be expected to materially affect fair value.

In August 2022, 8 733 538 Radius Health – Contingent Value Rights were allocated from a corporate action. In February 2025 BB Biotech received USD 1 per Right.

For assets and liabilities carried at amortised cost, their carrying values are a reasonable approximation of fair value.

Securities

The changes in value of securities at fair value through profit or loss by investment category are as follows (in CHF 1 000):

Listed shares

Unlisted shares

Derivative instruments

Total

Opening balance as at 01.01.2024 at fair values

2 619 989

14 725

2 634 714

Purchases

206 303

15 139

316

221 758

Sales

(561 097)

(42)

(561 139)

Gains/(losses) from securities

104 241

7 581

(274)

111 548

Realized gains

107 900

107 900

Realized losses

(46 182)

(274)

(46 456)

Unrealized gains

480 172

7 581

487 753

Unrealized losses

(437 649)

(437 649)

Closing balance as at 31.12.2024 at fair values

2 369 436

37 444

2 406 881

Opening balance as at 01.01.2025 at fair values

2 369 436

37 444

2 406 881

Purchases

399 037

12 079

411 116

Sales

(714 941)

(7 900)

(722 841)

Gains/(losses) from securities

131 471

(6 101)

8 004

133 375

Realized gains

162 350

7 900

170 250

Realized losses

(76 110)

(76 110)

Unrealized gains

240 414

104

240 518

Unrealized losses

(195 183)

(6 101)

(201 284)

Closing balance as at 30.09.2025 at fair values

2 185 004

43 422

104

2 228 530

Securities comprise the following:

Company

Number 31.12.2024

Change

Number 30.09.2025

Market price in original currency 30.09.2025

Valuation CHF mn 30.09.2025

Valuation CHF mn 31.12.2024

Ionis Pharmaceuticals

7 850 000

(1 625 162)

6 224 838

USD

65.42

324.3

249.0

Argenx SE

591 000

(55 678)

535 322

USD

737.56

314.4

329.8

Revolution Medicines

4 374 300

1 192 700

5 567 000

USD

46.70

207.0

173.6

Neurocrine Biosciences

1 820 000

(60 000)

1 760 000

USD

140.38

196.8

225.4

Alnylam Pharmaceuticals

760 000

(321 321)

438 679

USD

456.00

159.3

162.3

Vertex Pharmaceuticals

475 000

(17 200)

457 800

USD

391.64

142.8

173.6

Agios Pharmaceuticals

3 515 150

199 586

3 714 736

USD

40.14

118.8

104.8

Incyte

2 150 000

(714 145)

1 435 855

USD

84.81

97.0

134.7

Scholar Rock Holding

2 486 707

750 670

3 237 377

USD

37.24

96.0

97.5

Akero Therapeutics

2 382 755

2 382 755

USD

47.48

90.1

Immunocore

1 205 464

1 591 339

2 796 803

USD

36.33

80.9

32.3

Avidity Biosciences

2 152 862

2 152 862

USD

43.57

74.7

Celldex Therapeutics

3 071 615

486 054

3 557 669

USD

25.87

73.3

70.4

Beam Therapeutics

1 518 121

1 371 167

2 889 288

USD

24.27

55.8

34.2

Edgewise Therapeutics

1 428 929

1 347 068

2 775 997

USD

16.22

35.9

34.6

Relay Therapeutics

7 375 000

968 318

8 343 318

USD

5.22

34.7

27.6

Biohaven

2 040 853

762 000

2 802 853

USD

15.01

33.5

69.2

Wave Life Sciences

4 094 458

4 094 458

USD

7.32

23.9

46.0

Macrogenics

9 929 963

(9 971)

9 919 992

USD

1.68

13.3

29.3

Annexon

5 157 290

5 157 290

USD

3.05

12.5

24.0

Intra-Cellular Therapies

2 425 000

(2 425 000)

USD

n.a.

183.8

Moderna

1 600 000

(1 600 000)

USD

25.83

60.4

Arvinas

2 380 000

(2 380 000)

USD

8.52

41.4

Sage Therapeutics

4 460 693

(4 460 693)

USD

n.a.

22.0

Esperion Therapeutics

9 944 064

(9 944 064)

USD

2.65

19.9

Black Diamond Therapeutics

8 517 839

(8 517 839)

USD

3.79

16.5

Fate Therapeutics

4 839 779

(4 839 779)

USD

1.26

7.2

Blueprint Medicines

USD

n.a.

Listed shares

2 185.0

2 369.5

Rivus Pharmaceuticals

USD

43.4

37.4

Unlisted shares

43.4

37.4

Total shares

2 228.4

2 406.9

Blueprint Medicines – Contingent Value Right

284 900

284 900

USD

0.46

0.1

Molecular Templates – Warrants, 2.4.29

769 334

(769 334)

USD

n.a.

Radius Health – Contingent Value Right

8 733 538

(8 733 538)

USD

n.a.

Total derivative instruments

0.1

Total securities

2 228.5

2 406.9

4. Short-term borrowings from banks

4. Short-term borrowings from banks

At September 30, 2025, there is no short-term loan outstanding (December 31, 2024: CHF 117.5 mn at 0.90% p.a.).

5. Shareholders’ equity

5. Shareholders’ equity

The share capital of the Company consists of 55.4 mn fully paid registered shares (December 31, 2024: 55.4 mn) with a par value of CHF 0.20 each (December 31, 2024: CHF 0.20).

Treasury shares

The Company can buy and sell treasury shares in accordance with the Company’s articles of association and Swiss company law and in compliance with the listing rules of the SIX Swiss Exchange. During the period from January 1, 2025, to September 30, 2025, the Company has bought 166 750 treasury shares and has sold 554 000 treasury shares (01.01.–30.09.2024: Purchase of 20 000 treasury shares, no sales). As at September 30, 2025, the Company holds 250 750 treasury shares (December 31, 2024: 638 000 shares). The treasury shares as at September 30, 2025, were treated as a deduction from the consolidated shareholders’ equity using cost values of TCHF 8 169 (December 31, 2024: TCHF 39 640).

Share buyback 2nd line (bought for cancellation)

The Board of Directors has approved the repurchase of a maximum of 5 540 000 own registered shares with a nominal value of CHF 0.20 each. Until the end of the program at April 11, 2025, 250 750 registered shares were repurchased via a second trading line for the purpose of capital reduction (December 31, 2024: 84 000 shares).

6. Administrative expenses

6. Administrative expenses

Administrative expenses comprise the following:

in CHF 1 000

01.01.–30.09.2025

01.01.–30.09.2024

Investment manager

– Management fees

15 005

19 295

Personnel

– Board of Directors remuneration

1 245

1 250

– Wages and salaries

274

251

– Social insurance contributions and duties

105

100

16 629

20 896

The remuneration model of BB Biotech AG is determined by the Board of Directors.

Since 2014 the remuneration paid to the investment manager is based upon a 1.1% p.a. all-in fee on the average market capitalization without any additional fixed or performance-based elements of compensation. The compensation of the Board of Directors consists since 2014 of a fixed compensation.

7. Segment reporting

7. Segment reporting

The sole operating segment of the Group reflects the internal management structure and is evaluated on an overall basis. Revenue is derived by investing in a portfolio of companies active in the biotechnology industry for the purpose of capital appreciation. The following results correspond to the sole operating segment of investing in companies active in the biotechnology industry.

The geographical analysis of the profit/(loss) before tax is as follows – all income from financial assets are attributed to a country based on the domiciliation of the issuer of the instrument.

Profit/(loss) before tax in CHF 1 000

01.01.–30.09.2025

01.01.–30.09.2024

USA

182 777

(35 702)

Netherlands

14 470

97 442

Great Britain

5 710

(32 457)

Canada

(3 380)

Switzerland

(12 102)

(9 726)

Curaçao

(16 054)

(24 613)

Singapore

(22 089)

11 727

British Virgin Islands

(46 219)

13 009

106 493

16 300

8. Earnings per share

8. Earnings per share

01.01.–30.09.2025

01.01.–30.09.2024

Total comprehensive profit/(loss) for the period (in CHF 1 000)

106 448

16 243

Weighted average number of shares in issue

54 753 976

54 842 000

Earnings per share in CHF

1.94

0.30

Income used to determine diluted earnings per share (in CHF 1 000)

106 448

16 243

Weighted average number of shares in issue following the dilution

54 753 976

54 842 000

Diluted earnings per share in CHF

1.94

0.30

9. Assets pledged

9. Assets pledged

At September 30, 2025, securities in the amount of CHF 2 228.5 mn (December 31, 2024: CHF 2 406.9 mn) are collateral for a credit line of CHF 700 mn (December 31, 2024: CHF 700 mn). At September 30, 2025, there is no short-term loan outstanding (December 31, 2024: CHF 117.5 mn).

10. Transactions with the Investment Manager and related party transactions

10. Transactions with the Investment Manager and related party transactions

Detailed information regarding the remuneration model for the Board of Directors and the investment manager are mentioned under note «6. Administrative Expenses».

11. Commitments, contingencies and other off-balance sheet transactions

11. Commitments, contingencies and other off-balance sheet transactions

The Group had no commitments or other off-balance sheet transactions open at September 30, 2025 and December 31, 2024.

The operations of the Group are affected by legislative, fiscal and regulatory developments for which provisions are made where deemed necessary. The Board of Directors concludes that as at September 30, 2025, no proceedings existed which could have any material effect on the financial position of the Group (December 31, 2024: none).

12. Subsequent events

12. Subsequent events

There have been no events subsequent to September 30, 2025, which would affect the condensed consolidated interim financial statements.